MRI BRAIN Abnormalities in a Case of Spinocerebellar Ataxia (SCA)


Spinocerebellar ataxia (SCA) comprises of a group of neurodegenerative disorders characterized by progressive cerebellar ataxia (either alone or in combination with other neurological system involvement). They are currently classified into various subtypes based on the underlying genetic defect. Currently, there are about 40 subtypes of SCA, referred to as SCA 1, SCA2, ….SCA 40. MRIContinue reading “MRI BRAIN Abnormalities in a Case of Spinocerebellar Ataxia (SCA)”

“HOT CROSS BUN” Sign


Hot cross bun sign is typically seen in patients with multiple system atrophy (MSA). This refers to cruciform hyperintensity seen in pons (as seen in the left side FLAIR MRI image). The sign is due to selective loss of myelinated transverse pontocerebellar fibres and neurons in the pontine raphe, with preservation of the pontine tegmentumContinue reading ““HOT CROSS BUN” Sign”