OFATUMUMAB is MORE effective than TERIFLUNOMIDE in MULTIPLE SCLEROSIS


OFATUMUMAB is MORE EFFECTIVE than TERIFLUNOMIDE in MULTIPLE SCLEROSIS Multiple sclerosis (MS) is an autoimmune demyelinating disorder affecting optic nerves, brain and spinal cord. Treatment includes disease modifying treatments (DMTs) to reduce the number of relapses. In a recent study, ofatumumab was compared with teriflunomide in patients with relapsing remitting multiple sclerosis. Ofatumumab is anContinue reading “OFATUMUMAB is MORE effective than TERIFLUNOMIDE in MULTIPLE SCLEROSIS”

UNEXPECTED AND UNINTENDED BENEFITS OF LOCKDOWN


“UNEXPECTED & UNINTENDED BENEFITS” OF LOCKDOWN Dr Sudhir Kumar MD DM Apollo Hospitals, Hyderabad 25th May 2020 COVID-19 caused by SARS CoV2 virus is a pandemic that started from China and rapidly spread to about 200 countries worldwide. In the absence of a vaccine, strict lockdown was imposed in March 2020 to prevent a suddenContinue reading “UNEXPECTED AND UNINTENDED BENEFITS OF LOCKDOWN”

SMOKING REDUCES THE RISK OF PARKINSON’S DISEASE (PD)


Smoking is a risk factor for many non-communicable diseases, such as heart attacks, strokes, cancers, chronic obstructive lung diseases, liver disease, diabetes and pneumonia. It is expected to cause 1 billion deaths in 21st century. However, it has one benefit. In a long term study, smokers were found to have lower occurrence of Parkinson’s diseaseContinue reading “SMOKING REDUCES THE RISK OF PARKINSON’S DISEASE (PD)”

Life During COVID Times: A New Normal


Life during COVID Times: A New Normal?Dr Sudhir Kumar COVID-19 caused by SARS CoV2 virus is a pandemic, which started from China in December 2019, and since has rapidly spread to around 200 countries. After China, many European countries such as Italy, Spain and France saw huge numbers of COVID-19 cases and deaths due toContinue reading “Life During COVID Times: A New Normal”

Focal Status Epilepticus as a Presenting Symptom of SARS CoV2 Infection


Focal Status Epilepticus as a Presenting Symptom of SARS CoV2 Infection COVID 19, caused by SARS CoV2 virus is a global pandemic and has affected more than 3 million people worldwide. Most patients with COVID 19 present with respiratory symptoms, however, neurological involvement is not uncommon. Previously, stroke, Guillain Barre Syndrome, meningitis and encephalitis haveContinue reading “Focal Status Epilepticus as a Presenting Symptom of SARS CoV2 Infection”

HOW DOES COVID 19 AFFECT THE NERVOUS SYSTEM


How does COVID 19 affect Nervous System? Covid 19, caused by SARS CoV2 virus, is a global pandemic, which has infected about 1.88 million people in about 200 countries, resulting in about 1,16,800 deaths. Covid 19 predominantly affects respiratory system. Common symptoms include fever, cough, breathing difficulty, fatigue and chest pain. Severe cases manifest withContinue reading “HOW DOES COVID 19 AFFECT THE NERVOUS SYSTEM”

SMARTPHONE USE and PRIMARY HEADACHES


Smartphone use has increased over time. Smartphone is used for multiple functions other than phone, such as browsing internet, playing games, watching movies/videos, chatting, as a camera, etc. Life without smartphone is unimaginable. The impact of smartphone use on primary headache syndromes is not well known. In a recent research study, headache characteristics were comparedContinue reading “SMARTPHONE USE and PRIMARY HEADACHES”

GUILLAIN BARRE SYNDROME as a presenting feature of SARS CoV 2 INFECTION


Introduction Guillain Barre syndrome (GBS) refers to an acute onset polyradiculoneuropathy, which commonly manifests with rapidly progressive weakness of all 4 limbs, usually starting in lower limbs, then ascending to involve upper limbs. Muscle tone is reduced (hypotonia) and the deep tendon reflexes are either sluggish or absent. Minor sensory symptoms such as distal paresthesiaContinue reading “GUILLAIN BARRE SYNDROME as a presenting feature of SARS CoV 2 INFECTION”

POLYMINIMYOCLONUS


Polyminimyoclonus refers to involuntary, jerky, small amplitude, tremor-like movements, most commonly seen in hands. The commonest cause is degenerative anterior horn cell disease, commonly known as motor neuron disease or amyotrophic lateral sclerosis. These tremor-like movements (polyminimyoclonus) correspond to fasciculations in forearm muscles.

Jaw Tremors and Asymmetric hand Tremors in a Case of Essential Tremors


A 65-year old lady presented with six years history of tremors affecting both upper limbs, left more than right. I had periodically seen her during these 6 years. Tremors were of postural type and affected left upper limb more than the right upper limb. She developed jaw tremors for the past 3-6 months, which wereContinue reading “Jaw Tremors and Asymmetric hand Tremors in a Case of Essential Tremors”