SWI (GRE) Sequences are the BEST to Detect Bleed on MRI Brain


It is extremely vital that we differentiate brain hemorrhage (bleeding) from brain infarcts, when patients present with clinical features of stroke. This is because patients with infarcts are eligible to receive thrombolytic treatment, to lyse the blood clots. On the other hand, thrombolytic treatment is contraindicated in patients with brain hemorrhage (bleed). Drugs used for thrombolytic treatment, if administered to a patient with brain hemorrhage, could prove disastrous, as the hematoma can expand in size, and can prove fatal.

On a CT scan, it is easy to distinguish bleed from an infarct. Infarct is hypodense (black) and bleed is hyperdense (white) on CT scan.

On an MRI, it can get confusing. Both bleed and infarct can appear hyperintense (white) on DWI and FLAIR MRI images, as seen in the first MRI here. To sort out the diagnosis, GRE (SWI) sequences of MRI should be obtained. On SWI (GRE) sequences of MRI, there is suppression of signals in the area of bleed and it appears hypointense (black) as seen in the second MRI image here.

Published by Dr Sudhir Kumar MD (Medicine) DM (Neurology)

I am a doctor with 25 years experience. I have worked as a neurologist for about 20 years. Educating public and healthcare professionals is very dear to me. This is possible due to my interactions with thousands of patients and their caregivers. I salute the patients who suffer and it is our duty to minimise suffering by preventing diseases and ensuring prompt diagnosis and treatment of those already affected.

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