Tuberous sclerosis is a multi-systemic genetic disease, which predominantly manifests with seizures and cutaneous manifestations (such as adenoma sebaceum). Abnormalities on brain scan include cortical tubers, subependymal nodules (sually calcified) and subependymal giant cell astrocytoma (SEGA). MRI is usually preferred over CT scan as tubers and SEGAs are better appreciated on MRI as compared to CT.
Calcifications can be also be appreciated on MRI, especially susceptibility weighted images (SWI), as seen in mRI images above.
This child had only manifested with seizures of two years duration, which were well controlled with sodium valproate. He was doing well in studies.